![]() ![]() Once the test is completed, the used microchannel card is discarded and replaced with a new one. A few minutes after the sample is placed on the microchannel, a digital screen displays a viscosity reading that indicates whether the patient is at elevated risk for cardiac events. When the microchannel card is placed on a stage between a light source and a photodiode detector – a device that converts light into an electrical current – the device Lykotrafitis and Partola have developed measures how long it takes the blood to travel through the microchannel. The blood wicks into the microchannel and flows through a small groove using its own capillary pressure. A clinician places a droplet of blood onto a small card of transparent plastic containing a microchannel. This can be a complication for commercial instruments that are currently used to measure viscosity, but not for the device Lykotrafitis and Partola have developed. ![]() Since the velocity of our blood differs when pumping and at rest, its viscosity also changes. Blood behaves as a non-Newtonian fluid, which means that its viscosity changes depending on its velocity at any given time. Lykotrafitis and Partola’s device may be simple, but the science behind it is specialized and tailored to blood analysis. “With this information, doctors can suggest simple life-style changes on the spot to prevent their patients from having a stroke or heart attack.” “Our technology really is plug and play, but the impact is significant,” says Partola. The pair recently filed a provisional patent on their invention with the help of UConn’s Technology Commercialization Services. So Lykotrafitis and doctoral candidate Kostyantyn Partola developed a small electronic device that can measure blood viscosity at the point of care. “The research shows there is a connection between blood viscosity and cardiac events, and the equipment exists to test it, but not in a practical or efficient way. “We were very surprised that there is no commercial option to quickly and simply check this critical piece of information,” says associate professor of mechanical engineering and co-inventor, George Lykotrafitis. Yet despite this strong correlation, physicians can’t currently evaluate blood viscosity at routine office visits. In fact, one study found that increased blood viscosity is a more likely sign of a potential cardiac event than high blood pressure, gender, or smoking. Studies have shown that increased blood viscosity was significantly more prevalent in patients who experienced heart attacks and strokes compared to patients with lower blood viscosity. Thick blood also means organs and tissues receive less oxygen and may cause damage to the lining of blood vessels due to increased friction as blood travels throughout the body. In the case of blood, higher viscosity may signal potential problems, since the heart needs to work harder to pump sticky blood. Thick or sticky liquids like honey have high viscosity, while thin, watery liquids have low viscosity. Viscosity measures a fluid’s resistance to flow. But less attention has been paid to blood viscosity. From heart attacks to strokes, routine blood tests can screen for several types of life-threatening cardiac events. Doctors are often on the lookout for some common signs that might point to an issue, like abnormal cholesterol levels or high blood pressure. UConn researchers from the Department of Mechanical Engineering have developed a device that tests an important indicator of heart health that is often ignored – blood viscosity.īlood can be a window into the health of your heart. ![]()
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